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May 2010

Volume 14 Issue 3

The importance of pre-cleaned chromatography vials
By Loy Shick, Technical Services Manager, Thermo Fisher Scientific
Mass spectrometry is a powerful analytical technique commonly coupled with differing chromatography methods for sample separation. Since it is increasingly being adapted for more diverse applications, contamination issues affecting sensitivity and reproducibility must always be considered.

Design of experiments helps optimize pharmaceutical coating process
By Jerry Fireman
Upsher-Smith Laboratories faced a problem with a fluid bed coating process that produced inconsistent results. Many of the coating parameters interacted with each other, so conventional one-factor-at-a-time (OFAT) experiments were unable to resolve the issue.