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JANUARY 2008

Volume 11, Issue 1

Translational Medicine Translational Research: Bridging Science and Medicine
By Shawn Lawrence

Translational research has emerged as a key area of clinical R&D in Canadian hospitals and universities, where a focus on integrating drug discovery and development has become a priority. Typically the term translational research refers to the "translation" of basic research into real therapies for real patients and emphasizes a link between the laboratory and the patient’s bedside. In more defined terms, it is about taking basic research and discoveries made at the bench directly to the clinic.

Working together to expedite biologics development and improve availability: the production of pre-clinical grade biopharmaceuticals
By Bernard Massie and Denis Bourbeau

The pharmaceutical research paradigm is rapidly shifting from the traditional approach of screening for small chemical entities as potential drugs toward the development of biologics targeting novel untapped molecular targets and new mechanisms of action. In fact, it is estimated that 300 biologic products are in clinical trials, with another 600 to 700 in pre-clinical or early clinical development.

Unraveling a Puzzle That Has Mystified Science Researchers Worldwide
By Deanna Natalizio

Dr. Alan Bernstein is no stranger to the intricacies of health research.
As former director of Mount Sinai Hospital’s Research Institute and an
illustrious reign as president of the Canadian Institute for Health Research (CIHR) under his belt, his sights are now set on leading the world’s
latest strategy for the development of an HIV vaccine.

IT Makes Personalized Medicine a Reality
By Deanna Natalizio

Information Technology (IT) has revolutionized the way information is retrieved, transmitted, processed and stored. Its applications have altered industry of all types, becoming a catalyst for change through the creation of cutting edge technology and hastened access to information.

The Greening of Tomorrow's Energy
By Mike Pettapiece

In a McMaster University lab, biophysicist Duane Chung – along with fellow researchers at University of Waterloo – studies algae, one of the world’s most abundant aquatic plants in search of tomorrow’s fuels.